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. 2016 Feb 10;6:20922. doi: 10.1038/srep20922

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Copyright © 2016, Macmillan Publishers Limited

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Quantitative real-time PCR analysis of collagen type I (A), collagen type III (B), fibronectin (C) and elastin (D) as a function of pDCN, pIL-10 and pDCN+IL-10 polyplexes and time in culture (4 and 7 days). pDCN+IL-10 significantly (p < 0.001) suppressed collagen type I (A), collagen type III (B) and fibronectin (C) by at least 2-fold more than single pDCN or pIL-10 treatments. Similar inhibitory effect was not seen in the gene expression of elastin (D). Note: *indicates p < 0.001.