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. 2015 Nov 2;12:8. doi: 10.1186/s11556-015-0152-9

Table 2.

Summary of studies that analyze the effects of cycle ergometer training on metabolic outcomes

Outcomes
Metabolic outcomes
Author, year Mean age (years) Protocol type Body composition Metabolic disorders Endocrine function
Lovell et al. (2010) [27] 75.2 ± 0.8 CET
50–70 % of VO2max
30–45 min/session
3 sessions/week, 16 weeks
Training group:
↓ in body mass (from 78 ± 4.1 to 76 ± 4.2 kg).
↓ in % of body fat (from 29.2 ± 1 to 27.7 ± 1 %).
↔ in fat-free mass.
↔ in Control group.
Finucane et al. (2010) [37] 71.4 CET
50 to 70 % Pmax
60 min/session
3 sessions/week, 12 weeks
Training group:
↓ in weight loss (77.2 ± 16.1 to 77.0 ± 16.2 kg).
↓ in BMI (27.4 ± 4.9 to 27.3 ± 4.8 kg/m2).
↓ in waist circumference (98.6 ± 14.2 to 97.8 ± 13.8 cm).
↓ in intrahepatic lipid (3.7 ± 1.8 to 2.4 ± 1.0 %).
↔ in fat-free mass.
↔ in Control group.
↓ in fasting glucose, oral glucose insulin sensitivity and HbA1c in both groups.
Harber et al. (2009) [40] 71.1 CET
60 % of Pmax
20 to 40 min/session
3 sessions/week, 12 weeks
↓ in fat mass (from 27.6 ± 4.3 to 26.4 ± 4.1 kg).
↓ in % of body fat (from 40.7 ± 3.4 39.8 ± 3.5 %).
↑ in fat-free mass (from 39.2 ± 1.4 to 39.6 ± 1.4 kg).
↔ in body weight and BMI.
Coker et al. (2006) [33] 74 ± 1 CET
50 or 75 % of VO2max
40 min/session
4 to 5 sessions/week, 12 weeks
↔ in body weight and in % of body in MI and HI groups. ↑ in ISGD (5.0 ± 0.6 to 6.4 ± 0.5 mg/kg FFM/min) in HI group.
↔ in MI group.
↑ in non-oxidative glucose disposal in HI group (4.6 ± 0.6 to 6.0 ± 0.8 mg/kg FFM/min).
↔ in MI group.
Coker et al. (2009) [34] 71 ± 1 CET
50 or 75 % of VO2max
40 min/session
4 to 5 sessions/week, 12 weeks
↔ in body weight, BMI, and % of fat in MI and HI groups. ↔ in plasma adiponectin in MI and HI groups.
Lovell et al. (2012) [29] 75.2 ± 3.0 CET
50 to 70 % VO2max
30 to 45 min/session
3 sessions/week, 16 weeks
Training group:
↑ in the testosterone (16.9 ± 1.5 to 19.3 ± 1.8 nmol/L).
↑ in FT concentration (58.3 ± 4.9 to 67.2 ± 5.7 pmol/L).
↔ in GH, IGF-1 and SHBG concentration.
↔ in control group.
Sial et al. (1998) [46] 74 ± 2 CET
70 to 85 % HRmax
30 to 45 min/session
3 to 5 sessions/week, 16 weeks
↑ in fat free mass (from 49.4 ± 4.1 to 50.4 ± 4.6 kg). ↑ in the average rate of fat oxidation (from 1.6 ± 17 to 2.21 ± 28 µmol/min).
↓ in the average rate of carbohydrate oxidation (from 3.9 ± 483 to 3.2 ± 461 µmol/min).
↓ in the glucose Ra (from 1.1 ± 69 to 1.0 ± 95 µmol/min).
↔ in Ra and FFA rate of disappearance during exercise.
Zmuda et al. (1996) [50] 70 ± 4 CET
50 to 80 % HRR
60 min/session
1 session/day, 1 day
↑ in the serum testosterone, SHBG and total serum protein (39 %, 19 %, and 13 %, respectively; p < 0.01).
↑ in the FT (from 0.1 ± 0.04 to 0.2 ± 0.04).
↔ in the LH concentrations.
Perini et al. (2002) [41] 73.9 ± 3.5 CET
40 to 100 % of Pmax
60 min/session
3 sessions/week, 8 weeks
↔ in body weight and fat mass.

CET cycle ergometer training, VO 2max maximum volume of oxygen, P max maximal workload, HRR heart rate reserve, BMI body mass index, MI moderate intensity, HI high intensity, ISGD insulin-stimulated glucose disposal, FT free testosterone, GH growth hormone, IGF-1 insulin like growth factor-1, SHBG sex hormone-binding globulin, LH luteinizing hormone, R a glycerol rate of appearance, FFA free fatty acid, ↑ significant improvement within group, ↓ significant decrease within group, ↔ no change within group