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. 2016 Feb 10;36(1):e00296. doi: 10.1042/BSR20150205

Figure 6. SNX27 inhibits the migration of breast cancer cells.

Figure 6

(A) The mono-layer of MCF7 cells stably expressing GFP-SNX27 or GFP was wounded using a yellow tip. After 48 h, the cell migration was examined under the inverted microscope. It is observed that over-expression of SNX27 inhibits the cell migration. (B) Quantitative analysis of the migration speed by ImageJ software from three independent experiments represented in A, statistical analysis was assessed by t test. (C) MCF7 cells stably expressing shRNA-ctrl or shRNA-SNX27 were processed for wound healing assay as mentioned above. The results revealed that SNX27 knockdown promotes the cell migration. (D) Quantitative analysis of the migration speed by ImageJ software from three independent experiments represented in C, statistical analysis was assessed by t test.