Table 1. Parameter Values with 95% Confidence Limits in Parentheses and %VAF by Best-Fits of the Exponential Demand Curve Under Open and Closed Economies.
| Genotype | α parameter (×10−5) | Q0 parameter | %VAF |
|---|---|---|---|
| Open economy | |||
| D2R WT | 4.64 (3.84–5.43) | 18.0 (14.4–21.7) | 97.4 |
| D2R KO | 10.0a (6.72–13.4) | 22.6 (12.1–33.2) | 97.6 |
| D3R WT | 3.92 (3.59–4.25) | 19.9 (18.0–21.8) | 99.3 |
| D3R KO | 4.11 (3.54–4.67) | 23.1 (19.1–27.0) | 98.5 |
| D4R WT | 5.86 (3.95–7.77) | 16.3 (9.65–23.0) | 92.1 |
| D4R KO | 8.48a (6.57–10.4) | 21.1 (14.4–27.8) | 98.3 |
| Closed economy | |||
| D2R WT | 0.269 (0.181–0.356) | 222 (131–312) | 91.9 |
| D2R KO | 0.505a (0.407–0.604) | 225 (165–285) | 98.7 |
| D3R WT | 0.250 (0.179–0.321) | 279 (175–382) | 94.8 |
| D3R KO | 0.226 (0.171–0.282) | 299 (204–394) | 95.9 |
| D4R WT | 0.314 (0.188–0.439) | 239 (113–365) | 90.7 |
| D4R KO | 0.362 (0.178–0.547) | 221 (70.9–371) | 86.7 |
Abbreviations: KO, knockout; %VAF, percentage of variance accounted for; WT, wild type.
a
Significant difference from parameter value in WT littermate subjects.