Table 1.
Baseline comparison between patients with idiopathic normal pressure hydrocephalus and healthy controls
| INPH (n = 14) |
Healthy controls (n = 41) |
P value | |
|---|---|---|---|
| Age mean (SD) | 76.4 (5.1) | 70.5 (5.4) | 0.001* |
| Women n (%) | 6 (43) | 18 (44) | 1.0a |
| Previous MI n (%) | 0 (0) | 0 (0) | NA |
| Previous stroke n (%) | 0 (0) | 0 (0) | NA |
| Current smoking n (%) | 0 (0) | 2 (5) | 1.0a |
| Hypertensionb n (%) | 12 (86) | 28 (68) | 0.30a |
| Treated hyperlipidemia n (%) | 0 (0) | 6 (15) | 0.18a |
| 0–2 risk factorsc | 14 (100) | 41 (100) | NA |
| 3 risk factorsc | 0 (0) | 0 (0) | |
| Anti-platelet or anti-coagulant medication | 4 (29) | 0 (0) | 0.003a |
| MMT mean (range) | 26.6 (22–30) | 29.3 (28–30) | 0.002* |
INPH idiopathic normal pressure hydrocephalus, MI myocardial infarction, MMT mini mental test, SD standard deviation
* 2-sided t-test
a2-sided χ2-test
bDefined as either blood pressure > 140/90 or current use of blood pressure lowering medication
cRefers to current smoking, hypertension and treated hyperlipidemia