Table 2.
Treatment Regimen |
|||
---|---|---|---|
RSB | RSB + ALLP | ALLP | |
Time to PUA controlb | 4 hours | 4 hours | 27 hours |
PUA response ratec | 87% | 78% | 66% |
95% CI | 80% to 94% | 70% to 87% | 56% to 76% |
Abbreviations: PUA, plasma uric acid; RSB, rasburicase; ALLP, allopurinol; CI, confidence interval.
Data from Cortes et al.15
Time from initial medication administration to PUA level ≤7.5 mg/dL.
Defined as PUA level ≤7.5 mg/dL for all measurements from days 3 to 7, no unplanned extension of antihyperuricemic treatment, or missing samples (more than 2 consecutive samples or day 7 sample).