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. 2016 Feb 9;47:26. doi: 10.1186/s13567-016-0315-3

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© Burgess et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Lesion development over a 6 week period post-infestation with P. ovis across repeated vaccine trials. Lambs were infested with ~50 mites following immunisation with a seven recombinant protein cocktail vaccine with QuilA adjuvant (vaccine) or adjuvant only (control). Data on lesion size are presented on the transformed scale (cm, square root of lesion size). The plot shows observed lesion size of each lamb of vaccine (triangles) and control (circles) groups, estimated mean lesion size of vaccine (solid line) and control (dashed line) groups and corresponding 95% CIs envelop (shaded region).