Table 3.

Differences of IVIM parameters between different time points in locally advanced cervical cancer patients under concurrent chemo- radiotherapy (CCRT)

Variables	Time point 1 versus 2	Time point 1 versus 3	Time point 1 versus 4	Time point 2 versus 3	Time point 2 versus 4	Time point 3 versus 4
Diameter	<0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
D	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	0.016
ADC	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	0.879
f	0.002	< 0.001	0.005	0.408	0.337	0.047
D*	0.557	0.461	0.480	0.875	0.913	0.954

Data are shown as p value from each comparison. Time point 1, before CCRT within one week; time point 2, at the end of the second week of CCRT; time point 3, at the end of the first month of CCRT; time point 4, immediately after CCRT within one week

ADC apparent diffusion coefficient, D diffusion coefficient, f perfusion fraction, D* pseudo-diffusion coefficient