Table 2.
Univariate analyses of factors associated with corticosteroids responsiveness
| Response (n = 31,%) | Non-response (n = 16,%) | P value | |
|---|---|---|---|
| Age (years) | 65.8 (SD 9.5) | 67.1 (SD 14.2) | 0.21 |
| Sex male | 21 (67.4) | 13 (68.4) | 0.49 |
| NIHSS score | 9.0 (SD 3.2) | 9.3 (SD 2.8) | 0.50 |
| GCS score | 6.0 (SD 2.1) | 5.8 (SD 2.1) | 0.72 |
| Smoking | 12 (38.7) | 7 (43.6) | 0.76 |
| Excess alcohol consumption | 9 (29.0) | 5 (31.3) | 1.00 |
| Pre-existing illnesses | |||
| Hypertension | 22 (71.0) | 11 (68.9) | 0.90 |
| Diabetes | 16 (51.6) | 8 (50.0) | 0.17 |
| Coronary heart disease | 6 (19.4) | 3 (18.9) | 1.00 |
| Chest CT | |||
| GGOs | 23 (74.2) | 7 (43.8) | 0.04 |
| Consolidation opacities | 16 (51.6) | 9 (56.3) | 1.00 |
| Pleural effusions | 10 (32.3) | 4 (25.0) | 0.74 |
| Air bronchogram | 6 (19.4) | 4 (25.0) | 0.72 |
| PaO2/FiO2 (mmHg) | 139.5 (SD 55.5) | 147.0 (SD 63.0) | 0.99 |
| APACHE II score | 27.4 (SD 13.6) | 28.4 (SD 11.1) | 0.54 |
| pH value | 7.40 (SD 0.6) | 7.38 (SD 0.5) | 0.41 |
| Albumin (g/L) | 26.6 (SD 7.9) | 27.9 (SD 8.3) | 0.88 |
| Time from diagnosis to corticosteroids (days) | 5.5 (SD 2.0) | 6.0 (SD 2.5) | 0.16 |
Abbreviation: SD standard deviation, NIHSS National Institutes of Health Stroke Scale, GCS Glasgow Coma Scale, GGOs ground glass opacities, APACHE Acute Physiology and Chronic Health Evaluation, PaO 2 partial pressure of oxygen in arterial blood, FiO 2 fraction of inspired oxygen