Table 5.
Most frequent clinical manifestations in patients with SLE
| Clinical manifestation | Always positive PNC (n = 12 patients, 166 assessments) | Always negative PNC (n = 31 patients, 475 assessments) | Variable PNC (n = 26 patients, 459 assessments) |
|---|---|---|---|
| Glomerulonephritis | 31.9 % | 10.5 %a | 6.5 %a |
| Arthritis | 1.8 %b | 16.6 % | 6.1 %a,b |
| Mucocutaneous | 24.7 % | 21.3 % | 13.9 %a,b |
| Alopecia | 10.8 % | 7.8 % | 7.2 % |
| Hematologic | 3.0 %c | 1.1 %c | 7.0 %b |
| SLEDAI-2K >1 | 57.8 % | 48.8 % | 44.7 %a,b |
SLEDAI-2K Systemic Lupus Erythematosus Disease Activity Index 2000
aSignificant difference (p ≤ 0.05) compared with “Always positive PNC”
bSignificant difference (p ≤ 0.05) compared with “Always negative PNC”
cSignificant difference (p ≤ 0.05) compared with “Variable PNC”
The 69 patients are grouped depending on the outcome of PNC assay (positive or negative) over time