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. 2016 Feb 10;18:44. doi: 10.1186/s13075-016-0941-1

Table 6.

Temporal associations between occurrence of the most frequent clinical manifestations and positive PNC assay results

Clinical manifestation Occurrence of clinical manifestation
Same time as positive PNC After positive PNC
OR 95 % CI p Value OR 95 % CI p Value
Glomerulonephritis 1.48 0.95–2.31 0.080 1.41 0.80–2.50 0.233
Arthritis 0.72 0.39–1.34 0.303 0.36 0.16–0.82 0.015
Mucocutaneous 1.36 0.94–1.97 0.105 1.68 1.15–2.46 0.007
Alopecia 0.87 0.47–1.60 0.657 1.37 0.81–2.32 0.239
Hematological features 7.67 2.98–19.74 <0.001 0.59 0.28–1.26 0.173
SLEDAI-2K >0 1.27 0.86–1.88 0.222 1.24 0.83–1.85 0.288

OR odds ratio, CI confidence interval, PNC phagocytosis of necrotic cell material, SLEDAI-2K Systemic Lupus Erythematosus Disease Activity Index 2000