Table 3.
Hazard Ratios (HR) and 95 % Confidence Intervals (CI) of cancer mortality by quartiles of biomarkers and z-score
| Q1 | Q2 | Q3 | Q4 | P-trend | |
|---|---|---|---|---|---|
| Leukocyte Count | |||||
| No of Cases/Total | 62/672 | 54/638 | 79/630 | 92/630 | |
| Age-adjusted | 1.0 (ref) | 0.95 (0.66-1.37) | 1.48 (1.06-2.07) | 2.09 (1.52-2.89) | 0.01 |
| Multivariablea | 1.0 (ref) | 0.93 (0.65-1.34) | 1.38 (0.99-1.93) | 1.88 (1.36-2.62) | 0.04 |
| Multivariableb | 1.0 (ref) | 0.87 (0.60-1.25) | 1.20 (0.85-1.68) | 1.39 (0.98-1.97) | 0.42 |
| C-reactive protein | |||||
| No of Cases/Total | 61/639 | 73/643 | 75/645 | 78/643 | |
| Age-adjusted | 1.0 (ref) | 1.18 (0.84-1.66) | 1.37 (0.97-1.92) | 1.65 (1.18-2.31) | 0.02 |
| Multivariablea | 1.0 (ref) | 1.13 (0.80-1.59) | 1.25 (0.88-1.75) | 1.40 (0.99-1.99) | 0.12 |
| Multivariableb | 1.0 (ref) | 1.10 (0.78-1.55) | 1.12 (0.79-1.59) | 1.15 (0.81-1.64) | 0.43 |
| Z-score | |||||
| No of Cases/Total | 54/642 | 65/643 | 77/643 | 91/642 | |
| Multivariableb | 1.0 (ref) | 1.12 (0.78-1.61) | 1.30 (0.91-1.86) | 1.48 (1.03-2.14) | 0.09 |
aMultivariable model adjusted for age, examination year, alcohol intake, cardiorespiratory fitness and energy intake
bMultivariable model adjusted for age, examination year, alcohol intake, cardiorespiratory fitness, energy intake and smoking