Table 2.
Relationship of choroidal thickness with Alzheimer's type dementia (ATD) and mild cognitive impairment (MCI).
| Choroidal thickness (μm) | ATD (n = 82) | MCI (n = 76) | Controls (n = 88) | ∗ p value | ATD versus controls | MCI versus controls | ATD versus MCI | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean thickness (SD) | Mean thickness (SD) | Mean thickness (SD) | Mean difference (SE) | † p value | Mean difference (SE) | † p value | Mean difference (SE) | † p value | ||
| Subfoveal | 215.6 ± 64.5 | 228.7 ± 52.9 | 272.7 ± 60.1 | <0.001 | −57.1 (9.4) | <0.001 | −44.0 (9.6) | <0.001 | −13.1 (9.9) | 0.187 |
| Temporal 0.5 mm | 200.4 ± 60.0 | 211.0 ± 49.9 | 250.2 ± 55.3 | <0.001 | −49.7 (8.7) | <0.001 | −39.2 (8.9) | <0.001 | −10.5 (9.2) | 0.253 |
| Nasal 0.5 mm | 194.9 ± 63.4 | 204.7 ± 53.6 | 244.2 ± 60.5 | <0.001 | −49.3 (9.4) | <0.001 | −39.5 (9.6) | <0.001 | −9.7 (9.8) | 0.324 |
| Temporal 1.5 mm | 192.5 ± 59.3 | 198.3 ± 47.9 | 239.0 ± 53.4 | <0.001 | −46.5 (8.5) | <0.001 | −40.7 (8.6) | <0.001 | −5.7 (8.9) | 0.519 |
| Nasal 1.5 mm | 171.3 ± 64.3 | 182.7 ± 59.7 | 216.6 ± 68.4 | <0.001 | −45.3 (10.2) | <0.001 | −33.9 (10.4) | 0.001 | −11.3 (10.7) | 0.289 |
| Temporal 3 mm | 172.1 ± 50.1 | 174.4 ± 48.0 | 210.2 ± 43.9 | <0.001 | −38.1 (7.4) | <0.001 | −35.8 (7.6) | <0.001 | −2.2 (7.8) | 0.772 |
| Nasal 3 mm | 116.5 ± 39.2 | 120.0 ± 48.3 | 141.7 ± 52.8 | 0.002 | −21.7 (7.5) | 0.004 | −25.2 (7.6) | 0.001 | 3.5 (7.9) | 0.657 |
SD: standard deviation, SE: standard error, ∗ p value represents comparison among three groups, and † p value represents the pairwise comparison between two groups.
ANOVA.
Post hoc Bonferroni test.