. Author manuscript; available in PMC: 2016 Feb 10.

Published in final edited form as: NMR Biomed. 2008 Jun;21(5):473–478. doi: 10.1002/nbm.1211

Table 1.

Health assessment of rats for each of the different fraction dose cases. (iv denotes an intravenous injection in the tail, ip denotes an intraperitoneally injection.)

Fraction Course (mg/kg MnCl₂·4H₂0)	6 × 30	3 × 60	2 × 90	1 × 180
Observation Period (days)	12	6	4	2
Number of Rats Injected	6	6	4	5
Injection Route	iv	iv	ip	ip
Weight	Early loss. Later gain.	Early loss.	Early loss.	Early loss.
Deaths	0	0	0	1
Injection site complications.	None.	Occasional abdominal induration.	Occasional tail necrosis.	Consistent tail necrosis.
Appearance.	Normal.	Normal.	Normal.	Rumpled and hunched.
Activity	Normal.	Normal.	Normal.	Lethargic.