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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Free Radic Biol Med. 2015 Nov 24;90:252–260. doi: 10.1016/j.freeradbiomed.2015.11.026

Figure 5. OA-NO2 decreases the Ang II-induced fibrotic processes in heart tissue.

Figure 5

The expression of M-CSFR (a), iNOS (b), and arginase-I (c) was detected in heart tissue of C57BL/6J mice treated for 2 weeks with Ang II (1.5 ng/g/min) and OA-NO2 (6 mg/kg) via subcutaneously implanted osmotic minipumps. The concentration of TGF-β was determined in plasma samples (n=6-9) (d). The pictures represent one of several individual experiments (n=6-9). A *p value of less than 0.05 was considered significant when evaluating differences between the individual bars and positive control (Ang II-treated mice).