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. Author manuscript; available in PMC: 2016 Feb 10.
Published in final edited form as: Neurosurgery. 2009 Jan;64(1):4–14. doi: 10.1227/01.NEU.0000335776.93176.83

FIGURE 2.

FIGURE 2

Photomicrographs illustrating that neurological disorders often have distinct boundaries that differentiate them from normal nervous tissue. A, the reticulin border of a pituitary adenoma (arrows) can be used as a capsule in isolating the adenoma for proteomic analysis, while excluding the normal pituitary gland. B, a blood vessel surrounding a high-grade glioma can be used to analyze the unique proteins associated with glioma vasculature. This can then be used to characterize proteins that are unique to a particular glioma subtype or grade.