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Data presented here indicate that both EGL-20/Wnt and MAB-5/Hox are required to inhibit anterior migration of QL.a/p. EGL-20 might immediately inhibit QL.a/p anterior migration via an “acute” mechanisms independent of BAR-1/β-catenin and MAB-5/Hox, as well as through a later “maintenance” phase that requires BAR-1 and MAB-5 and might require changes in gene expression. MAB-5 might also promote posterior migration.
