Table 2. Specificity and sensitivity of five differentially methylated genes between AC and SCC.

Gene	Specificity [95% CI]	Sensitivity [95% CI]	AUC [95% CI]
CDH13	0.74 [0.65, 0.81]	0.49 [0.38, 0.59]	0.68 [0.64, 0.72]
APC	0.65 [0.55, 0.74]	0.60 [0.44, 0.74]	0.66 [0.62, 0.70]
CDKN2A	0.55 [0.47, 0.63]	0.37 [0.29, 0.45]	0.45 [0.41, 0.49]
MGMT	0.60 [0.52, 0.68]	0.32 [0.27, 0.37]	0.40 [0.35, 0.44]
RUNX3	0.86 [0.75, 0.92]	0.47 [0.42, 0.51]	0.47 [0.42, 0.51]