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. 2016 Feb 10;11(2):e0148510. doi: 10.1371/journal.pone.0148510

Fig 3. Effects of the PPAR-δ agonist GW610742 on angiogenesis.

Fig 3

Representative images from the sham-operated (Sham), myocardial infarction alone (MI), and MI treated with GW610742 (MI + GW) groups on day 7 (A) and day 14 (B) post-surgery. Images using Masson’s trichrome staining (MT) show vessels (arrows) in the heart post-operation. The immunoreactivity and positive cell numbers for CD31 and Ki-67 (arrows) were counted in each group post-operation. Values are represented as the mean ± the standard error of the mean (SEM). *P < 0.05 and vs. **P < 0.01 the corresponding MI group. Scale bars = 100 μm and 50 μm for MT, CD31, and Ki-67 staining, respectively. Sham (n = 3/each day), MI (n = 7/each day), MI + GW (n = 7/each day).