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. 2016 Feb 10;11(2):e0148784. doi: 10.1371/journal.pone.0148784

Table 1. The five measured perfusion parameters in the RT-alone and AART groups.

Parameter RT (n = 5) AART (n = 4) P-value
Kep 0.0002 (0.0001, 0.0049) 0.00006 (0.00003, 0.00012) 0.190
Kel 0.0062 (0.0032, 0.0214) 0.0490 (0.0202, 0.0753) 0.063
Splat/TTP 0.0049 (0.0035, 0.0061) 0.0107 (0.0078, 0.0142) 0.016
AH 9.40 (1.85, 162.3) 794.05 (201.13, 1958.61) 0.063
MER 1.49 (1.354, 1.6126) 1.81 (1.7488, 1.8925) 0.016

The data are medians with the interquartile ranges in parentheses. RT, radiation therapy; AART, SU11248 plus RT; Kep (sec -1), exchange rate constant from the extracellular space back to the plasma in the vascular structure; Kel (sec -1), elimination rate constant from the plasma to the renal excretion; Splat, signal intensity in the plateau; TTP, time to peak enhancement; AH, constant corresponding to the size of the interstitial space; and MER, maximum enhancement ratio.