Fig 3. Results from analysis of aCGH data.

a) Relationship between Shar Pei and Alaskan Malamute mean log₂ ratios for 157 copy number variable sites in the dog genome. AMY2B mean log₂ ratio is plotted in red, and deviates significantly from the null distribution. b) Histogram of residuals from linear regression performed on mean log₂ ratios from aCGH data in the Alaskan Malamute and Shar Pei. Value of residuals appears on the x-axis while density, or proportion of a specific residual occurring, falls on the y-axis. The residual for mean log₂ ratio in AMY2B is indicated in red and falls 5.86 standard deviations away from the mean (0±.2).