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Baseline [11C]PiB PET in F198S and P102L asymptomatic carriers. Baseline (left) and follow-up (right) [11C]PiB SUVR images for 3 asymptomatic carriers (2 P102L (A, B), 1 F198S (C)). No appreciable increase in [11C]PiB from the baseline to the follow-up scan was observed in any of the participants. (D) Quantitation of mean [11C]PiB SUVR in the cortical grey matter and whole cerebellum supported this qualitative observation.
