Table 1.

Demographic characteristics and baseline neuropsychological and motor performance

	NC (n = 9)	AC (n = 4)	SC (n = 1)	p
Age	66.1 (4.2)	44.3 (11.7)	41	< 0.001
Gender (Male, Female)	3, 6	1, 3	0, 1	0.312
Education	16.7 (1.7)	14 (1.4)	13	< 0.001
Mutation Status (F198S, P102L)	0, 0	1, 3	1, 0	n.a.
MMSE *	28.9 (1.0)**	29.5 (0.6)	27	0.364
CDR-SB	0.1 (0.2)	0 (0.0)	6	0.933
COWA *	45.7 (8.0)***	44 (6.1)	22	0.968
Finger Tapping (Dom)	n.a.	49.5 (8.8)	26	n.a.
Finger Tapping (Non-Dom)	n.a.	43.3 (8.8)	24	n.a.
Grooved Pegboard (Dom)	n.a.	70.3 (8.1)	154	n.a.
Grooved Pegboard (Non-Dom)	n.a.	80.3 (17.0)	149	n.a.

Mean (standard deviation). NC = non-carrier; AC = asymptomatic carrier; SC = symptomatic carrier; MMSE = Mini-Mental State Examination; CDR-SB = Clinical Dementia Rating-Sum of Boxes; COWA = Controlled Oral Word Association; n.a. = not available; Dom = dominant hand; Non-Dom = non-dominant hand).

^*Covaried for age, gender, and education;

^**Missing one non-carrier value;

^***Missing three non-carrier values.