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. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Bioorg Med Chem. 2015 Nov 30;24(2):160–178. doi: 10.1016/j.bmc.2015.11.043

Figure 6. Efficacies of Rce1 inhibitors for Ste24 and FTase.

Figure 6

A) Compounds were evaluated at 10 μM using the fluorescence-based CaaX proteolysis assay measuring the percent activity remaining. Yeast cells expressed either HsRce1 or HsSte24. Error bars show SD. B) Indicated compounds were evaluated at 10, 25, and 50 μM using the fluorescence-based FTase assay. Error bars show SD.