Table 4.
P2X7R genotype distribution and allele frequency in elite athletes with multiple stress fractures
| SNP | Genotype | Multiple stress fracture (%) |
|---|---|---|
| rs208294 | CC | 47 (98) |
| TC | 1 (2) | |
| TT | 0 | |
| P = | 0.7 | |
| Allele frequency | C | 0.99 |
| T | 0.01 | |
| P = | 0.37 | |
| rs1718119 | GG | 23 (50) |
| GA | 21 (46) | |
| AA | 2 (4) | |
| P = | 0.04* | |
| Allele frequency | G | 0.64 |
| A | 0.36 | |
| P = | <0.01* | |
| rs2230912 | AA | 32 (70) |
| GA | 14 (30) | |
| GG | 0 (0) | |
| P = | 0.55 | |
| Allele frequency | A | 0.84 |
| G | 0.16) | |
| P = | 0.64 | |
| rs3751143 | AA | 31 (67) |
| AC | 13 (28) | |
| CC | 2 (4) | |
| P = | 0.66 | |
| Allele frequency | A | 0.82 |
| C | 0.19 | |
| P = | 0.58 | |
| rs1653624 | TT | 47 (98) |
| TA | 1 (2) | |
| AA | 0 (0) | |
| P = | NA | |
| Allele frequency | T | 0.99 |
| A | 0.01 | |
| P = | NA |
P values are the result of comparisons between genotype and allele frequencies between the multiple stress fracture and non-stress fracture cohorts
*Significance at P < 0.05 in comparison to the non-stress fracture elite athlete group