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. 2016 Mar;78:53–62. doi: 10.1016/j.vph.2015.11.040

Table 2.

Effect of SNC-Fc on human saphenous vein organ culture model.

Fc SNC-Fc
Intimal area/length of vein segment (μm) 8.68 ± 1.85 1.28 ± 0.60
% intimal cells BrdU positive 30.4 ± 7.2 13.6 ± 3.6
% medial cells BrdU positive 11.6 ± 3.1 5.0 ± 1.3
Medial density (cell/m2 × 1000) 14.13 ± 3.3 15.44 ± 2.8
Migration into intima (non-BrdU cells/length × 1000) 2.9 ± 2.0 2.5 ± 0.8
% intimal cells ISEL positive 6.23 ± 1.6 3.06 ± 0.73
% medial cells ISEL positive 3.18 ± 0.60 1.95 ± 0.22
Endothelial coverage (fold change from Fc) 1 ± 0 2.92 ± 0.68
% endothelial cells ISEL positive 9.44 ± 1.58 3.49 ± 1.0

Mean ± SEM.

Indicates a significant difference from the Fc control sample, paired Student's t-test, p < 0.05, n = 5.