Table 1.

Cerebellar firing patterns.

DOI: http://dx.doi.org/10.7554/eLife.11102.016

	WT	lamb1t normal	p, norm. vs. WT	lamb1t abnormal	p, abnorm. vs. WT	p, norm vs. abnorm.
Deep cerebellar nuclei neurons
# of cells	26	42		56
average f.r.	37.4 ± 3.7	50.3 ± 5.9	0.3499	26.7 ± 2.9	0.0109	0.0029
predominant f.r.	61.0 ± 6.9	110.1 ± 13.8	0.0004	221.9 ± 20.9	<0.0001	0.0001
CV ISI	0.677 ± 0.05	0.751 ± 0.05	0.6542	1.272 ± 0.07	<0.0001	<0.0001
Purkinje neurons
# of cells	61	76		45
average f.r.	62.9 ± 2.8	73.6 ± 2.8	0.0052	62.7 ± 5.0	0.3400	0.0619
predominant f.r.	83.2 ± 3.4	98.7 ± 3.6	0.0141	103.8 ± 8.1	0.0128	0.4462
CV ISI	0.578 ± 0.02	0.531 ± 0.01	0.3036	0.919 ± 0.07	<0.0001	<0.0001

Means and significance of firing rates and coefficients of variation. Definitions: f.r., firing rate. CV ISI, coefficient of variation of the interspike interval; that is, variability. The data are means ± SEM, and the p values were determined by the Kolmogorov-Smirnov test for non-parametric distributions, which can be seen in Figure 8. N = 3 WT and N = 4 lamb1t mice; n for each class of cell recording is given in the table.