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. 2016 Jan;7(1):16–28. doi: 10.1177/1947603515595837

Figure 3.

Figure 3.

Histological assessment of cartilage repair using the International Cartilage Repair Society (ICRS) II scoring system. White and black bars represent microfracture (MFx) and BST-CarGel, respectively. P values are shown for differences in means (±SE) between BST-CarGel and MFx. Parameters are shown in order of ascending P values from left to right. BST-CarGel treatment resulted in a significant improvement of structural parameters Surface Architecture and Surface/Superficial Assessment at 13 months posttreatment, and trended (P < 0.11) for Cell Morphology, Basal Integration, and Overall Assessment. No histological parameters were improved significantly for the MFx group over the BST-CarGel group. All biopsies received scores of 100 for Inflammation, which indicate an absence of inflammation. BST-CarGel n = 20 except for Chondrocyte Clustering, Abnormal Calcification, Matrix Staining, Vascularization, Tissue Morphology, and Inflammation where n = 21; MFx n = 17.