Biopsy histology of the best (A), median (B), and worst (C) repairs of the BST-CarGel and microfracture (MFx) groups at 13 months posttreatment, according to the International Cartilage Repair Society (ICRS) II parameter Overall Assessment. The median repairs represent the 11th of 21 and 9th of 17 highest scores for BST-CarGel and MFx, respectively. The BST-CarGel biopsies show superior tissue quality and organization compared with the MFx biopsies for both the best and median repairs. The worst biopsies in each group were very similar with comparable thicknesses, smooth articulating surfaces, and were mainly composed of fibrous tissue. Scale bars = 1 mm.