Skip to main content
. 2016 Feb 11;6:20766. doi: 10.1038/srep20766

Figure 1. The crystallography structure of PTP1B.

Figure 1

PTP1B has an active site Cysteine 215 with surrounding catalytic loop (a) and a previous identified allosteric site (b) which is surrounded by α3 helix, α6 helix and α7 helix. During PTP1B activation, WPD loop (c) moves from the open position to the closed position.