Table 2. Demographic and CMR parameters for non-obese and obese subjects.
| Non-obese (n=63) | Obese (n=65) | P-value | |
|---|---|---|---|
| Demographic data | |||
| Age (year) | 50.7±16.7 | 51.3±13.6 | 0.80 |
| Gender (% male) | 52 | 46 | 0.60 |
| Height (m) | 1.70±0.11 | 1.70±0.10 | 0.89 |
| Weight (kg) | 76.8±13.2 | 100.2±14.8 | <0.0001 |
| BMI (kg m−2) | 26.4±2.7 | 34.7±4.6 | <0.0001 |
| BSA (m2) | 1.90±0.22 | 2.17±0.20 | <0.0001 |
| Office SBP (mm Hg) | 171.9±30.0 | 169.6±30.1 | 0.66 |
| Office DBP (mm Hg) | 98.1±16.0 | 96.9±14.9 | 0.66 |
| Heart rate (b.p.m.) | 72.1±16.2 | 71.9±12.1 | 0.91 |
| No. of antihypertensives | 2.6±1.9 | 3.1±1.9 | 0.13 |
| ACEi/ARB (%) | 71.4 | 76.9 | 0.55 |
| CCB (%) | 49.2 | 56.9 | 0.48 |
| β-Blocker (%) | 33.3 | 38.5 | 0.58 |
| Diuretic (%) | 55.5 | 72.3 | 0.07 |
| CMR data | |||
| LVEF (%) | 66.2±8.3 | 70.1±9.3 | <0.05 |
| LV mass (g) | 142.8±42.5 | 177.0±57.6 | <0.0005 |
| Indexed LV mass (g m−2) | 57.3±13.9 | 71.4±20.5 | <0.0001 |
| Maximal wall thickness (mm) | 12.4±2.9 | 14.1±2.8 | <0.005 |
| Asymmetric wall thickness (%) | 22.2 | 33.8 | 0.17 |
| Cardiac output (l min−1) | 6.8±1.7 | 8.2±2.1 | <0.0001 |
Abbreviations: ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BMI, body mass index; BSA, body surface area; b.p.m., beats per minute; CCB, calcium channel blocker; CMR, cardiac magnetic resonance; DBP, diastolic blood pressure; LV, left ventricular; LVEF, left ventricular ejection fraction; SBP, systolic blood pressure.