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. 2016 Feb 11;6:20896. doi: 10.1038/srep20896

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(A) 5-Fu/P85 copolymer micelles could inhibit metastases in liver by general observation. (B,C) Calculation of tumor volume and weight. (D)A low frequency of lesions in 5-Fu/P85 group was observed by H&E staining (Optical microscope × 200 magnification, N:normal tissue, T:tumor tissue). (The concentration of 5-Fu was 1 mg/kg for 5-Fu/P85 copolymer micelle. *P < 0.05; **P < 0.01).