Table 6. Association between C677T MTHFR genotype and AAA according to baseline characteristics.

Subgroup	AAA group (n)	Control groups (n)		CC	OR, 95% CI	P Value	P Value for Interaction
	TT/CT	CC	TT/CT
Age							0.06
<70 yr	50	18	113	28	0.69 (0.35, 1.36)	0.28
≥70 yr	75	12	132	37	1.75 (0.86, 3.56)	0.12
Sex							0.08
Male	113	25	215	61	1.28 (0.76, 2.15)	0.35
Female	12	5	30	4	0.32 (0.073, 1.40)	0.13
Smoking Habits							0.12
No	15	8	112	31	0.52 (0.20, 1.34)	0.17
Yes	110	22	133	34	1.28 (0.71, 2.31)	0.42
Drinking Habits							0.006
No	55	21	150	35	0.61 (0.33, 1.14)	0.12
Yes	70	9	95	30	2.46 (1.10, 5.50)	0.03
Hypertension							0.11
No	36	11	138	29	0.69 (0.31, 1.51)	0.35
Yes	89	19	107	36	1.58 (0.85, 2.94)	0.15
Dyslipidaemia							0.23
No	60	19	197	52	0.83 (0.46, 1.52)	0.55
Yes	65	11	48	13	1.60 (0.66, 3.88)	0.30
Type 2 diabetes							0.46
No	109	28	208	56	1.05 (0.63, 1.74)	0.86
Yes	16	2	37	9	1.95 (0.38, 10.04)	0.43
CAD							0.60
No	81	21	177	53	1.15 (0.65, 2.04)	0.62
Yes	44	9	68	12	0.86 (0.34, 2.22)	0.76
Ischemic stroke							0.93
No	101	25	220	59	1.08 (0.64, 1.83)	0.76
Yes	24	5	25	6	1.15 (0.31, 4.28)	0.83
PAD							0.46
No	84	20	208	51	1.03 (0.58, 1.83)	0.92
Yes	41	10	37	14	1.55 (0.62, 3.91)	0.35
Hcy							0.19
HHcy	101	15	132	23	1.17 (0.58, 2.36)	0.66
nHcy	24	15	113	42	0.60 (0.29, 1.24)	0.17

CI, confidence interval; OR, odds ratio.

MTHFR, methylenetetrahydrofolate reductase; CAD, coronary artery disease; PAD, peripheral arterial disease; HHcy, hyperhomocysteinaemia ; nHcy, normal serum homocysteine level.