Table 2. Laboratory values and markers of subclinical cardiovascular (CV) disease at the time of non-invasive CV testing in the RRI-CKD cohort (n=198).
| Mean ± SD or median (IQR) | |
|---|---|
| Indices of renal function | |
| Serum creatinine (mg/dL) | 2.3 (1.3) |
| Estimated glomerular filtration rate (mL/min/1.73 m2) | 29 ± 12 |
| Blood urea nitrogen (mg/dL) | 42.0 ± 20.1 |
| Traditional coronary risk factors | |
| Total cholesterol (mg/dL) | 190 ± 50 |
| Low-density lipoprotein (mg/dL) | 105 ± 39 |
| High-density lipoprotein (mg/dL) | 43 ± 17 |
| Triglycerides (mg/dL) | 148 ± 87 |
| Systolic blood pressure (mmHg) | 137 ± 24 |
| Diastolic blood pressure (mmHg) | 74 ± 14 |
| Pulse pressure (mmHg) | 63 ± 21 |
| Heart rate (bpm) | 65 ± 11 |
| Novel risk factors | |
| Serum total calcium (mg/dL) | 9.2 ± 0.6 |
| Serum phosphorous (mg/dL) | 3.8 ± 0.9 |
| Serum albumin (mg/dL) | 4.0 ± 0.5 |
| Hematocrit (%) | 36.2 ± 4.7 |
| Intact parathyroid hormone (ng/mL) | 117 (148) |
| C-reactive protein (mg/L) | 2.0 (5.5) |
| Urine albumin/creatinine ratio (mg/g) | 158 (835) |
| Markers of subclinical CVD | |
| Maximum carotid intima-medial thickness† (mm) | 1.21 (1.04) |
| Mean carotid intima-media thickness† (mm) | 0.85 (0.44) |
| Flow mediated dilation (%) | 3.3 ± 4.2 |
| Pulse wave velocity (m/s) | 9.1 ± 2.9 |
| Left ventricular mass index (g/m2) | 103 (41) |
| Coronary calcification score | 32 (499) |
| Heart rate variability: low/high frequency ratio | 2.5 (2.7) |
| Heart rate variability: SDNN (ms) | 101 (51) |
SDNN = standard deviation of all normal R-R (NN) intervals; SD = standard deviation; IQR = interquartile range. †Estimated CV (SD/sample mean) for the max and mean intima-medial thickness was 0.85/1.46 = 0.59, and 0.37/0.93 = 0.39, respectively.