Table 4.
T0 | T1 | T8 | |
---|---|---|---|
Amino acids | |||
Alanine | 1.00 ± 0.04 | 1.22 ± 0.06* | 1.48 ± 0.12* |
Alanine | 1.00 ± 0.05 | 0.73 ± 0.03* | 1.92 ± 0.14* |
Asparagine | 1.00 ± 0.13 | 0.61 ± 0.07* | 0.51 ± 0.05* |
Aspartic acid | 1.00 ± 0.05 | 0.74 ± 0.07* | 1.07 ± 0.14 |
Butyric acid, 4-amino | 1.00 ± 0.06 | 0.62 ± 0.10* | 0.59 ± 0.09* |
Cysteine | 1.00 ± 0.16 | 0.83 ± 0.10 | 0.94 ± 0.11 |
Glutamic acid | 1.00 ± 0.05 | 0.94 ± 0.05 | 0.67 ± 0.06* |
Glutamine | 1.00 ± 0.07 | 0.66 ± 0.06* | 0.76 ± 0.10 |
Isoleucine | 1.00 ± 0.04 | 1.31 ± 0.08* | 1.73 ± 0.13* |
Lysine | 1.00 ± 0.05 | 0.71 ± 0.05* | 0.89 ± 0.08 |
Methionine | 1.00 ± 0.05 | 2.29 ± 0.14* | 2.30 ± 0.18* |
Phenylalanine | 1.00 ± 0.08 | 1.67 ± 0.05* | 1.24 ± 0.07 |
Proline | 1.00 ± 0.05 | 2.01 ± 0.09* | 1.53 ± 0.12* |
Pyroglutamic acid | 1.00 ± 0.03 | 0.71 ± 0.04* | 0.63 ± 0.07* |
Serine | 1.00 ± 0.05 | 4.23 ± 0.21* | 7.17 ± 0.47* |
Threonine | 1.00 ± 0.03 | 1.71 ± 0.09* | 2.69 ± 0.15* |
Valine | 1.00 ± 0.07 | 1.03 ± 0.04 | 1.36 ± 0.08* |
Organic acids | |||
Benzoic acid | 1.00 ± 0.04 | 1.13 ± 0.08 | 1.08 ± 0.05 |
Citric acid | 1.00 ± 0.29 | 1.30 ± 0.59 | 0.95 ± 0.35 |
Dehydroascorbic acid | 1.00 ± 0.09 | 1.43 ± 0.41 | 1.46 ± 0.34 |
Fumaric acid | 1.00 ± 0.05 | 1.56 ± 0.23 | 3.13 ± 0.27* |
Galactonic acid | 1.00 ± 0.05 | 0.85 ± 0.04 | 0.99 ± 0.08 |
Glyceric acid | 1.00 ± 0.05 | 2.11 ± 0.17* | 4.99 ± 0.36* |
Lactic acid | 1.00 ± 0.12 | 0.94 ± 0.09 | 1.01 ± 0.17 |
Malic acid | 1.00 ± 0.05 | 1.08 ± 0.20 | 2.02 ± 0.22* |
Nicotinic acid | 1.00 ± 0.06 | 1.00 ± 0.05 | 0.93 ± 0.05 |
Phosphoric acid | 1.00 ± 0.26 | 0.98 ± 0.30 | 0.96 ± 0.30 |
Succinic acid | 1.00 ± 0.03 | 0.84 ± 0.08 | 0.53 ± 0.05* |
Sugars | |||
Lyxose | 1.00 ± 0.06 | 1.13 ± 0.02 | 1.32 ± 0.05* |
Fructose | 1.00 ± 0.02 | 2.59 ± 0.14* | 0.81 ± 0.04* |
Fucose | 1.00 ± 0.05 | 1.00 ± 0.04 | 0.93 ± 0.04 |
Glucose | 1.00 ± 0.08 | 1.28 ± 0.06* | 0.61 ± 0.04* |
Glucose, 1,6-anhydro | 1.00 ± 0.08 | 1.63 ± 0.08* | 1.67 ± 0.12* |
Inositol | 1.00 ± 0.04 | 0.87 ± 0.04 | 0.73 ± 0.04* |
Sorbitol | 1.00 ± 0.05 | 0.91 ± 0.05 | 1.09 ± 0.09 |
Sucrose | 1.00 ± 0.05 | 1.51 ± 0.14* | 1.27 ± 0.17 |
Others | |||
Mannopyranoside, 1-O-methyl- | 1.00 ± 0.07 | 1.09 ± 0.03 | 0.94 ± 0.07 |
Ornithine | 1.00 ± 0.10 | 1.84 ± 0.09* | 1.30 ± 0.15 |
Putrescine | 1.00 ± 0.09 | 1.12 ± 0.07 | 1.57 ± 0.08* |
Spermidine | 1.00 ± 0.16 | 2.47 ± 0.18* | 4.11 ± 0.45* |
Threitol | 1.00 ± 0.05 | 0.78 ± 0.05* | 0.78 ± 0.05 |
Data are normalized to the mean response calculated for the time point (T0) of each measured batch. Values are presented as the mean ± SE of 6 biological determinations. Asterisks at T1 and T8 indicate values significantly different from T0, as calculated by t test (increase and decrease) with p-value < 0.01