Table 3.
Multivariate survival statistics
| Multivariate N = 1874 |
Comparison | Hazard ratio | 95% Confidence interval | p* |
|---|---|---|---|---|
| Age | <0.0001 | |||
| Unit = 10 years | 1.134 | 1.083–1.189 | ||
| Facility type | 0.0042 | |||
| Comprehensive vs. | Academic | 1.159 | 1.046–1.285 | 0.0048 |
| Community vs. | Academic | 1.192 | 0.963–1.476 | 0.1074 |
| Other vs. | Academic | 1.568 | 1.092–2.252 | 0.0149 |
| Community vs. | Comprehensive | 1.028 | 0.828–1.276 | 0.8014 |
| Grade | <0.0001 | |||
| 2 vs. | 1 | 1.448 | 1.210–1.732 | <0.0001 |
| 3 vs. | 1 | 1.795 | 1.490–2.164 | <0.0001 |
| 4 vs. | 1 | 2.862 | 1.738–4.711 | <0.0001 |
| Tumor size | <0.0001 | |||
| 2–5 cm vs. | <2 cm | 1.422 | 1.206–1.676 | <0.0001 |
| >5 cm vs. | <2 cm | 1.725 | 1.424–2.089 | <0.0001 |
| >5 cm vs. | 2-5 cm | 1.213 | 1.070–1.376 | 0.0026 |
| Node status | <0.0001 | |||
| 1–3 | Negative | 1.300 | 1.164–1.453 | <0.0001 |
| >3 | Negative | 1.632 | 1.415–1.883 | <0.0001 |
| >3 | 1–3 | 1.256 | 1.098–1.435 | 0.0009 |
| Margin status | <0.0001 | |||
| R1 vs. | R0 | 1.470 | 1.274–1.695 | <0.0001 |
| R2 vs. | R0 | 1.858 | 1.241–2.74 | 0.0027 |
| Not specified vs. | R0 | 1.318 | 1.100–1.581 | 0.0028 |
| R2 vs. | R1 | 1.264 | 0.831–1.93 | 0.2730 |
| Adjuvant Rx | <0.0001 | |||
| Chemo vs. | Chemo + Rads | 1.131 | 0.971–1.317 | 0.1133 |
| Rads vs. | Chemo + Rads | 1.566 | 1.170–2.096 | 0.0026 |
| No adjuvant Rx vs. | Chemo + Rads | 1.767 | 1.582–1.973 | <0.0001 |
*Paired comparisons are statistically significant after controlling for multiple comparisons when p < 0.0170 for 3 comparisons and p < 0.0127 for 4 comparisons. Thus, note that facility type “Other vs. Academic” is not statistically significant.