Table 2.
II-A. Univariate survival – Patient characteristics | Median (months) | 3 Yr (%) | 5 Yr (%) | p |
---|---|---|---|---|
Overall survival | ||||
n = 881 | 26.6 | 41.5 | 27.1 | |
Univariate demographics | ||||
Age (10 years), HR (95% CI) | 1.02 (0.96, 1.09) | 0.5100 | ||
Gender | <0.0001 | |||
Male | 31.3 | 37.4 | 20.0 | |
Female | 21.3 | 44.7 | 33.0 | |
Comorbidities | 0.0468 | |||
None | 30.8 | 44.50 | 31.43 | |
One or more | 21.1 | 36.61 | 27.07 | |
II-B. Univariate tumor characteristics | Median (months) | 3 Yr (%) | 5 Yr (%) | p |
Grade | <0.0001 | |||
1–2 | 32.3 | 46.9 | 31.8 | |
3–4 | 21.4 | 33.7 | 19.4 | |
Surgical margin | <0.0001 | |||
Negative | 31.0 | 45.4 | 30.4 | |
Micro or macro positive | 19.6 | 29.4 | 14.1 | |
Involved – not specified | 15.3 | 27.3 | 14.8 | |
Regional nodes examined | 0.0108 | |||
0 | 29.0 | 45.4 | 30.2 | |
1–3 | 29.1 | 43.0 | 28.1 | |
≥4 | 21.4 | 30.7 | 17.7 | |
Lymph nodes positive | <0.0001 | |||
0 | 36.5 | 50.5 | 34.7 | |
1–3 | 15.0 | 18.1 | 5.8 | |
4–11 | 15.4 | 10.5 | 0.0 | |
Tumor size | 0.0004 | |||
<5 cm | 40.2 | 54.1 | 36.3 | |
≥5 cm | 23.8 | 37.9 | 24.3 | |
II-C. Univariate – operative outcome | Median (months) | 3 Yr (%) | 5 Yr (%) | p |
Length of stay (10 fold increase), HR(95% CI) | 2.13 (1.35, 3.36) | 0.0012 | ||
Readmission 30 days | 0.3494 | |||
None | 29.0 | 43.5 | 31.7 | |
Readmission | 26.6 | 37.7 | 22.3 | |
II-D. Univariate adjuvant therapy | Median (months) | 3 Yr (%) | 5 Yr (%) | p |
Systemic treatment | 0.2177 | |||
Chemotherapy only | 22.6 | 36.8 | 18.8 | |
Chemotherapy and radiation | 27.8 | 44.3 | 22.0 | |
None | 27.8 | 42.5 | 30.5 |
Missing data reported in Table 1. Kaplan–Meier curves of categorical variables compared with log rank test of homogeneity or trend test for 3 or more ordered levels. Continuous variables tested with Cox proportion hazards regression. HR, hazard ratio.