Table 2.
Pre-term outcome overall and for HIV + ve only
| All women | Bivariate | Multivariable iv | ||||
|---|---|---|---|---|---|---|
| Variable | Term n (% i) |
Pre-term <37w) n (%) |
p-value ii | 0R iii (95 % CI) | 0R (95 % CI) | adj p-value |
| Year | ||||||
| 2011 | 3409 (78.03) | 960 (21.97) | 0.002 | 1 (ref) | 1 (ref) | |
| 2014 | 4412 (80.54) | 1066 (19.46) | 0.86 (0.78–0.95) | 0.94 (0.83–1.06) | 0.291 | |
| Age Category | ||||||
| < 18 | 643 (77.75) | 184 (22.25) | 0.053 | 1 (ref) | 1 (ref) | |
| 18–24 | 3421 (78.54) | 935 (21.46) | 0.96 (0.8–1.14) | 0.92 (0.77–1.1) | 0.362 | |
| 25–34 | 2945 (80.42) | 717 (19.58) | 0.85 (0.71–1.02) | 0.78 (0.64–0.94) | 0.01 | |
| > 34 | 726 (81.3) | 167 (18.7) | 0.8 (0.64–1.02) | 0.73 (0.57–0.93) | 0.012 | |
| Mode of Delivery | ||||||
| Vaginal | 5365 (80.27) | 1319 (19.73) | <0.001 | 1 (ref) | 1 (ref) | |
| Emergency Caesarean | 1100 (75.5) | 357 (24.5) | 1.32 (1.15–1.51) | 1.3 (1.12–1.51) | 0.001 | |
| Planned Caesarean | 1346 (79.69) | 343 (20.31) | 1.04 (0.91–1.18) | 1.07 (0.93–1.24) | 0.319 | |
| HIV | ||||||
| Negative | 4820 (81.47) | 1096 (18.53) | <0.001 | 1 (ref) | 1 (ref) | |
| Positive | 2893 (77.71) | 830 (22.29) | 1.26 (1.14–1.4) | 1.33 (1.19–1.48) | <0.001 | |
| Unregistered Antenatal | 102 (51) | 98 (49) | 4.23 (3.18–5.62) | 4.24 (3.18–5.64) | <0.001 | |
| HIV + ve women only | Bivariate | Multivariable v | ||||
| Variable | Term n (% i) |
Pre-term (<37w) n (%) |
p-value ii | 0R (95 % CI) | 0R (95 % CI) | adj p-value |
| Year | ||||||
| 2011 | 1249 (77.19) | 369 (22.81) | 0.51 | 1 (ref) | 1 (ref) | |
| 2014 | 1644 (78.1) | 461 (21.9) | 0.95 (0.81–1.11) | 0.63 (0.27–1.44) | 0.269 | |
| Age Category | ||||||
| < 18 | 69 (74.19) | 24 (25.81) | 0.849 | 1 (ref) | 1 (ref) | |
| 18–24 | 925 (77.8) | 264 (22.2) | 0.82 (0.51–1.33) | 1.14 (0.32–4.01) | 0.84 | |
| 25–34 | 1482 (77.88) | 421 (22.12) | 0.82 (0.51–1.32) | 1.26 (0.36–4.4) | 0.717 | |
| > 34 | 395 (78.37) | 109 (21.63) | 0.79 (0.48–1.32) | 1.35 (0.36–5) | 0.655 | |
| Mode of Delivery | ||||||
| Vaginal | 1940 (78.51) | 531 (21.49) | 0.13 | 1 (ref) | 1 (ref) | |
| Emergency Caesarean | 420 (74.6) | 143 (25.4) | 1.24 (1.01–1.54) | 1.43 (1–2.06) | 0.05 | |
| Planned Caesarean | 526 (77.47) | 153 (22.53) | 1.06 (0.87–1.3) | 0.82 (0.49–1.37) | 0.456 | |
| CD4 category | ||||||
| < 200 | 274 (80.35) | 67 (19.65) | 0.582 | 1 (ref) | 1 (ref) | |
| 201–350 | 282 (82.22) | 61 (17.78) | 0.88 (0.6–1.3) | 0.87 (0.58–1.29) | 0.478 | |
| 351–500 | 275 (81.36) | 63 (18.64) | 0.94 (0.64–1.37) | 0.92 (0.6–1.39) | 0.686 | |
| > 500 | 136 (77.27) | 40 (22.73) | 1.2 (0.77–1.87) | 1.16 (0.72–1.88) | 0.545 | |
| ART regimen | ||||||
| Nil ARVs | 100 (67.57) | 48 (32.43) | 0.002 | 1 (ref) | 1 (ref) | |
| AZT/NVP | 778 (79.88) | 196 (20.12) | 0.52 (0.36–0.77) | 0.2 (0.08–0.51) | 0.001 | |
| D4T/3TC/NVP | 685 (75.52) | 222 (24.48) | 0.68 (0.46–0.98) | 0.21 (0.08–0.55) | 0.001 | |
| EFV/TDF/FTC | 1315 (78.93) | 351 (21.07) | 0.56 (0.39–0.8) | 0.31 (0.11–0.9) | 0.031 |
i row percentage, ii Chi-square, iii Odds Ratio, iv following variables were adjusted for in the multivariable adjusted model, year age group, mode of delivery, pregnancy term category, HIV status
i Chi-square, ii AZT/NVP vs D4T/3TC/NVP p-value = 0.714, iii AZT/NVP vs FTC p-value = 0.321, iv D4T/3TC/NVP vs FTC p-value = 0.368, v following variables were adjusted for in the multivariable adjusted model, year age group, mode of delivery, pregnancy term category, HIV status, CD4 (HIV positive mothers only), ART regimen (HIV positive mothers only)