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. 2016 Feb 11;18:46. doi: 10.1186/s13075-016-0939-8

Table 5.

Biometric models and chi-square test statistics, sex adjusted

Model MZ prevalence DZ prevalence MZ rho DZ rho MZ cwc DZ cwc H Variance component estimates Chi-square test statistics
A D C E LL –2ln df p value AIC
Sat 0.03 (0.03–0.04) 0.03 (0.03–0.04) 0.79 (0.59–0.90) 0.70 (0.50–0.83) 0.44 (0.28–0.62) 0.35 (0.22–0.51) 0.18 (0.00–0.62) –10014.6 3.87 1 Compare CE, p = 0.05 20,037.10
ACE 0.03 (0.03–0.04) 0.03 (0.03–0.04) 0.79 (0.59–0.90) 0.70 (0.50–0.83) 0.44 (0.28–0.62) 0.35 (0.22–0.51) 0.18 (0.0–0.62) 0.18 (0.0–0.62) 0.61 (0.25–0.97) 0.21 (0.06–0.36) –10014.5 44.6 1 Compare AE, p <0.0001 20,037.10
ADE 0.03 (0.03–0.04) 0.03 (0.03–0.04) 0.83 (0.68–0.91) 0.41 (0.36–0.47) 0.49 (0.35–0.64) 0.16 (0.13–0.19) 0.83 (0.72–0.94) 0.83 (0.72–0.94) 0 0.17 (0.06–0.28) –10036.8 0 1 Compare AE, p = 1.0 20,081.66
AE 0.03 (0.03–0.04) 0.03 (0.03–0.04) 0.83 (0.68–0.91) 0.41 (0.36–0.47) 0.49 (0.35–0.64) 0.16 (0.13–0.19) 0.83 (0.72–0.94) 0.83 (0.72–0.94) 0.17 (0.06–0.28) –10036.8 34.3 1 Compared ACE, p <0.0001 20,079.66
CE 0.03 (0.03–0.04) 0.03 (0.03–0.04) 0.74 (0.61–0.83) 0.74 (0.61–0.83) 0.39 (0.29–0.51) 0.39 (0.29–0.51) 0.74 (0.63–0.85) 0.26 (0.15–0.37) –10016.5 3.87 1 Compare ACE, p = 0.05 20,038.97
DE 0.03 (0.03–0.04) 0.03 (0.03–0.04) 0.82 (0.66–0.91) 0.20 (0.17–0.23) 0.48 (0.33–0.63) 0.08 (0.07–0.09) 0.81 (0.70–0.94) 0.82 (0.70–0.94) 0.18 (0.06–0.30) –10067.7 61.7 1 Compare ADE, p <0.0001 20,141.35

A additive genetic, AIC Akaike’s Information Criterion, C common environment, cwc case-wise concordance rate, D dominant genetic, df degrees of freedom, DZ dizygotic, E unique environment, H broad sense heritability, LL = log likelihood of model, –2ln = Likelihood Ratio chi-square test, MZ monozygotic, rho tetrachoric correlation coefficient, Sat saturated model.

The ACE model in bold displayes the best model fit by the AIC. Fixing the common environmental component C at zero produced a significantly worse fit (p <0.0001).