Table 1.
Results from DAVID clustering analysis of GO terms for genes activated by Ribbon based on microarray data.
| Annotation cluster (enrichment score) | GO term | Fold enrichment | P-value |
|---|---|---|---|
| 1 (5.34) | DNA metabolic process | 3.5 | 1.0E-09 |
| DNA repair | 4.3 | 2.7E-07 | |
| Response to DNA damage stimulus | 4.0 | 3.6E-07 | |
| Cellular response to stress | 3.2 | 1.6E-06 | |
| DNA repair | 4.1 | 6.4E-03 | |
| DNA damage | 3.9 | 8.4E-03 | |
| 2 (2.42) | Nuclear chromosome part | 4.3 | 8.5E-05 |
| Nuclear chromosome | 3.8 | 2.3E-04 | |
| DNA replication | 2.9 | 2.6E-03 | |
| DNA-dependent DNA replication | 3.3 | 1.1E-02 | |
| DNA replication initiation | 6.2 | 2.4E-02 | |
| Origin recognition complex | 10.5 | 3.0E-02 | |
| Nuclear origin of replication recognition complex | 10.5 | 3.0E-02 | |
| 3 (2.37) | Nuclear chromosome part | 4.3 | 8.5E-05 |
| Nuclear chromosome | 3.8 | 2.3E-04 | |
| Chromosomal part | 2.3 | 2.8E-04 | |
| Intracellular non-membrane-bounded organelle | 1.5 | 3.5E-04 | |
| Non-membrane-bounded organelle | 1.5 | 3.5E-04 | |
| Replication fork | 7.8 | 7.6E-04 | |
| Nuclear replisome | 10.2 | 1.0E-03 | |
| Nuclear replication fork | 10.2 | 1.0E-03 | |
| Replisome | 10.2 | 1.0E-03 | |
| Chromosome | 2.0 | 1.1E-03 | |
| DNA replication | 2.9 | 2.6E-03 | |
| Homologous recombination | 5.7 | 2.7E-03 | |
| Protein-DNA complex | 4.4 | 4.4E-03 | |
| Nucleotide excision repair | 3.7 | 4.4E-03 | |
| Mismatch repair | 5.1 | 4.6E-03 | |
| DNA replication | 3.3 | 1.5E-02 | |
| DNA-directed DNA polymerase activity | 4.8 | 1.8E-02 | |
| DNA polymerase activity | 4.6 | 2.1E-02 | |
| DNA polymerase complex | 9.2 | 3.9E-02 | |
| 4 (2.09) | Nuclear lumen | 1.8 | 1.6E-03 |
| Membrane-enclosed lumen | 1.6 | 2.2E-03 | |
| Organelle lumen | 1.6 | 2.6E-03 | |
| Intracellular organelle lumen | 1.6 | 2.6E-03 | |
| Nucleoplasm | 1.6 | 6.9E-02 | |
| 5 (2.08) | Stress response | 7.1 | 7.8E-05 |
| Stress-induced protein | 12.8 | 3.4E-04 | |
| Heat shock | 12.8 | 3.4E-04 | |
| Response to heat | 3.8 | 5.9E-04 | |
| Heat shock-mediated polytene chromosome puffing | 18.6 | 7.4E-04 | |
| Polytene chromosome puffing | 18.6 | 7.4E-04 | |
| Response to hypoxia | 7.3 | 1.0E-03 | |
| Response to oxygen levels | 7.3 | 1.0E-03 | |
| Response to temperature stimulus | 3.5 | 1.0E-03 | |
| Cellular response to heat | 15.5 | 1.4E-03 | |
| Chaperone HSP70 | 8.1 | 2.2E-03 | |
| Heat shock protein 70, conserved site | 8.2 | 2.3E-03 | |
| Heat shock protein Hsp70 | 7.6 | 3.2E-03 | |
| Heat shock protein 70 | 7.6 | 3.2E-03 | |
| Molecular chaperone | 8.8 | 4.2E-02 | |
| Response to protein stimulus | 8.7 | 4.3E-02 |