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. Author manuscript; available in PMC: 2016 Feb 11.
Published in final edited form as: Ann Otol Rhinol Laryngol. 2015 Jun 15;124(11):893–902. doi: 10.1177/0003489415590657

Table 2.

Pepsin-mediated elevation of IL1β and PTGS2 (COX-2) in esophageal cells in vitro.

Fold Change* p-value
IL1β protein expression
0.1mg/ml Pepsin (1hr) 1.99 0.0211
0.1mg/ml Pepsin (20hr) 2.12 0.0159
PTGS2 (COX-2) gene expression
0.1mg/ml Pepsin (1hr) 2.06 0.0006
0.1mg/ml Pepsin (20hr) 1.96 0.0018
0.1mg/ml Pepsin, pH4 (5min) 1.98 0.0013
No Pepsin, pH4 (5min) 2.11 0.0003
*

Relative to Control