TABLE 3.
FISH probe sets
| Probe set | Genomic target | Reagent name | Chromosomal location | Fluor |
|---|---|---|---|---|
| I | Chromosome 1 centromere | CEP 1 (D1Z5) | 1p11.1-q11.1 Alpha Satellite DNA | SpectrumOrange |
| Chromosome 6 centromere | CEP 6 (D6Z1) | 6p11.1-q11 Alpha Satellite DNA | SpectrumAqua | |
| Chromosome 11 centromere | CEP 11 (D11Z1) | 11p11.11-q11 Alpha Satellite DNA | SpectrumGreen | |
| KRAS gene | LSI KRAS | 12p12.1 | SpectrumGold | |
| II (UroVysion) | Chromosome 3 centromere | CEP 3 | 3p11.1-q11.1 Alpha Satellite DNA | SpectrumRed |
| Chromosome 7 centromere | CEP 7 | 7p11.1-q11.1 Alpha Satellite DNA | SpectrumGreen | |
| CDKN2A gene | LSI p16 | 9p21 | SpectrumGold | |
| Chromosome 17 centromere | CEP 17 | 17p11.1-q11.1 Alpha Satellite DNA | SpectrumAqua |
CDKN2A, cyclin-dependent kinase inhibitor 2A; KRAS, Kirsten rat sarcoma viral oncogene homolog.