Table 3.
Changes in functional class and echocardiographic parameters in CRT non-responders (left) and CRT responders (right)
| CRT non-responders (n = 63) |
CRT responders (n = 89) |
|||||
|---|---|---|---|---|---|---|
| Before CRT | 6 months with CRT | P-value | Before CRT | 6 months with CRT | P-value | |
| NYHA class | 2.8 ± 0.4 | 2.2 ± 0.5 | <0.001 | 2.8 ± 0.5 | 2.1 ± 0.5 | <0.001 |
| EF (%) | 27 ± 9 | 28 ± 10 | 0.37 | 27 ± 9 | 40 ± 12 | <0.001 |
| ESV index (mL/m2) | 68 ± 32 | 70 ± 32 | 0.08 | 71 ± 30 | 42 ± 23 | <0.001 |
| GLS (%) | −8.3 ± 4.3 | −7.9 ± 4.2 | 0.46 | −8.6 ± 3.6 | −9.7 ± 4.8 | 0.02 |
| GCS (%) | −11.3 ± 3.8 | −12.8 ± 4.4 | 0.004 | −11.2 ± 3.1 | −14.9 ± 4.3 | <0.001 |
| MD (ms) | 115 ± 44 | 87 ± 34 | <0.001 | 125 ± 55 | 80 ± 32 | <0.001 |
CRT, cardiac resynchronization therapy; EF, ejection fraction; ESV, end-systolic volume; GCS, global circumferential strain; GLS, global longitudinal strain; MD, mechanical dispersion; NYHA, New York Heart Association.