Table 2.
Odds ratios (ORs) and 95% confidence intervals (Cls) of overall and sub-sites of colorectal cancer risk in relation to history of diabetes mellitus (DM)
| Site (for cases) | Men (n=2599) |
Women (n=1196) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| No. of participants | No.of DM (%) | Age-adjusted OR2 (95% CI) | Multivariate1 OR2 (95% CI) | No. of participants | No. of DM (%) | Age-adjusted OR2 (95% CI) | Multivariate1 OR2 (95% CI) | ||
| Controls | 1878 | 184 (9.8) | 1.00 (reference) | 1.00 (reference) | 897 | 53 (5.9) | 1.00 (reference) | 1.00 (reference) | |
| Cases | Overall | 721 | 113 (15.7) | 1.47 (1.13, 1.90) | 1.53 (1.16, 2.01) | 349 | 40 (11.5) | 1.92 (1.24, 2.98) | 1.95 (1.20, 3.17) |
| Proximal | 137 | 21 (15.3) | 1.44 (0.88, 2.37) | 1.50 (0.90, 2.50) | 77 | 8 (10.4) | 1.59 (0.72, 3.52) | 1.74 (0.76, 4.00) | |
| Distal | 210 | 43 (20.5) | 2.02 (1.39, 2.95) | 2.06 (1.40, 3.04) | 129 | 15 (11.6) | 2.02 (1.09, 3.74) | 1.97 (1.03, 3.79) | |
| Rectum | 374 | 49 (13.1) | 1.19 (0.84, 1.68) | 1.25 (0.87, 1.79) | 143 | 17 (11.9) | 2.04 (1.13, 3.67) | 2.02 (1.07, 3.82) | |
1
Adjusted for age, body mass index, alcohol consumption, overcooked meat consumption and physical activity.
2
OR estimates for overall colorectal cancer by binary logistic regression and subsite specific colorectal cancer by polytomous logistic regression.