Table 7.
Urinary L-FABP levels predictive of AKI in the open-repair study
| Time point | Cutoff value (μg/g Cr) | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|
| Preoperation | 12.7 | 0.25 | 0.81 | 0.12 | 0.91 |
| After anesthesia induction | 9.9 | 0.42 | 0.69 | 0.12 | 0.92 |
| Pre-AXC | 5.6 | 0.83 | 0.42 | 0.13 | 0.96 |
| 1 h post-AXC | 37.2 | 0.50 | 0.79 | 0.20 | 0.94 |
| 2 h post-AXC | 173.0 | 0.67 | 0.83 | 0.30 | 0.96 |
| Postoperation | 32.3 | 0.92 | 0.54 | 0.17 | 0.98 |
| 4 h postoperation | 348.5 | 0.50 | 0.92 | 0.40 | 0.95 |
| POD1 | 112.1 | 0.62 | 0.83 | 0.28 | 0.95 |
| POD2 | 48.6 | 0.54 | 0.83 | 0.25 | 0.95 |
| POD3 | 19.5 | 0.85 | 0.61 | 0.19 | 0.97 |
L-FABP liver-type fatty-acid-binding protein, AKI acute kidney injury, AXC aorta cross-clamping, PPV positive predictive value, NPV negative predictive value, POD postoperative day, Cr creatinine