Table 5.

Sensitivity, specificity, PPV^a, NPV^b, LHR^c (positive) and LHR (negative) of dichotomised (high/low) values of perfusion parameters at baseline and there combinations.

Perfusion parameters	Prognostic accuracy (%)	Sensitivity		Specificity		PPV		NPV		LHR (positive)		LHR (negative)
		%	95% CId	%	95% CI	%	95% CI	%	95% CI	Estimate	95% CI	Estimate	95% CI
Highe BFf (n = 12)	83.3	83.3	55.2–95.3	83.3	55.2–95.3	83.3	55.2–95.3	83.3	55.2–95.3	5.0	1.8–13.9	0.20	0.07–0.55
High BVg (n = 11)	62.5	58.3	32.0–80.7	66.7	39.1–86.2	63.6	35.4–84.8	61.5	35.5–82.3	1.8	0.9–3.5	0.63	0.37–1.05
Lowh MTTi (n = 13)	62.5	66.7	39.1–86.2	58.3	32.0–80.7	61.5	35.5–82.3	63.6	35.4–84.8	1.6	1.0–2.7	0.57	0.29–1.14
Low PSj (n = 12)	58.3	58.3	32.0–80.7	58.3	32.0–80.7	58.3	32.0–80.7	58.3	32.0–80.7	1.4	0.8–2.5	0.71	0.40–1.29
High BF & high BV (n = 9)	70.8	58.3	32.0–80.7	83.3	55.2–95.3	77.8	45.3–93.7	66.7	41.7–84.8	3.5	1.1–11.4	0.50	0.32–0.77
High BF and low MTT (n = 8)	75.0	58.3	32.0–80.7	91.7	64.6–98.5	87.5	52.9–97.8	68.8	44.4–85.8	7.0	0.8–60.7	0.45	0.30–0.68
High BF and low PS (n = 6)	75.0	50.0	25.4–74.6	100.0	75.8–100.0	100.0	61.0–100.0	66.7	43.8–83.7	Undefined	Undefined	0.50	0.36–0.69

^aPositive predictive value.

^bNegative predictive value.

^cLikelihood ratio.

^dConfidence interval.

^eHigh > median value.

^fBlood flow (ml/100 g/min).

^gBlood volume (ml/100 g).

^hLow (≤median value).

ⁱMean transit time (s).

^jPermeability surface (ml/100 g/min).