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. 2015 Dec 10;183(3):341–349. doi: 10.1111/cei.12728

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Enhancement of expression of inducible nitric oxide synthase (iNOS) in arthritic cardiac tissue. (b) The collagen‐induced arthritis (CIA) group presents increase in the expression of iNOS compared to the control group (a). Immunolabelling in cardiomyocytes (black arrow) and in the arteriole endothelium (red arrow). (c) Control of reaction (CR). Counterstain: haematoxylin. Bars: 20 μm. (d) Densitometric analysis (arbitrary units, a.u.). Bars express mean ± standard deviation (n = 6; one‐way analysis of variance (anova) followed by Bonferroni's post‐test; ***P < 0·0001).