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Transverse T1-weighted muscle MRI images of a clinically presymptomatic patient. On the thigh level (upper and middle images), the adductor magnus muscles show severe fatty alterations. The vastus intermedius, adductor longus, semimembranosus and biceps femoris muscles are only mildly or moderately affected by lipomatous alterations. Lower leg muscles (lower image) are spared and show no pathologic changes.
