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Time-kill curves of M. avium IWGMT49 exposed to clofazimine and amikacin (a to d) and clofazimine and clarithromycin (e to h), alone and combined at 2× MIC, 1× MIC, 0.5× MIC, and 0.25× MIC of each drug. Modest killing was observed with most combinations, except with the paired combination consisting of 2× MIC of amikacin and clofazimine. Errors bars represent SDs from the replicates.
