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. 2016 Jan 29;60(2):990–1002. doi: 10.1128/AAC.02017-15

FIG 6.

FIG 6

In silico model of GIM-1 Y233N with hydrolyzed ampicillin in the active site and the GIM-1 Y233N model superimposed on the model of native GIM-1. (A and B) A closeup of the active site in the in silico model of the GIM-1 Y233N mutant (cyan/magenta) (A) and of the model of the GIM-1 Y233N mutant superimposed on wild-type GIM-1 (gray/yellow) with hydrolyzed ampicillin (AMP) (B). (C) Superimposition of the model of GIM-1 (gray; PDB accession number 2YNW.B) and that of GIM-1 Y233N (green backbone and cyan side chains) showing the movement of the L1 and L3 loops. Red spheres, water molecules; orange spheres, zinc ions.